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Application of laser capture microdissection in genetic analysis of neuroblastoma and neuroblastoma precursor cells

✍ Scribed by Katleen De Preter; Jo Vandesompele; Pierre Heimann; Mark M. Kockx; Mireille Van Gele; Jasmien Hoebeeck; Els De Smet; Martine Demarche; Geneviève Laureys; Nadine Van Roy; Anne De Paepe; Frank Speleman


Book ID
117467735
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
398 KB
Volume
197
Category
Article
ISSN
0304-3835

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✍ Massimo Romani; Paola Scaruffi; Ida Casciano; Katia Mazzocco; Crocifissa Lo Cuns 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 French ⚖ 122 KB

The tp73 gene, a tp53 homologue, has been sub-regionally mapped at 1p36.3, a chromosomal region frequently deleted in neuroblastoma. Due to its chromosomal localization and to the mono-allelic expression observed in some neuroblastoma cell lines, it was proposed that tp73 might be involved in the pa