Application of ion-exclusion and ion-exchange techniques in preparing α,β-dihydroxyisobutyramide and α,β-dihydroxyisobutyric acid from acetol via the cyanohydrin synthesis

Application of ion-exclusion and ion-exc

Application of ion-exclusion and ion-exchange techniques in preparing 2,3-dihydroxy-2-methylbutanamide and 2,3-dihydroxy-2-methylbutanoic acid from acetoin via the cyanohydrin synthesis

✍ J.E. Powell; S. Kulprathipanja; D.A. Johnson; H.R. Burkholder 📂 Article 📅 1972 🏛 Elsevier Science 🌐 English ⚖ 387 KB

The techniques of ion exclusion and ion exchange have been exploited to obtain substantial yields of 2,3-dihydroxy-z-methylbutanamide and z,S-dihydroxy-zmethylbutanoic acid, respectively, following acid hydrolysis of acetoin cyanohydtin. The reaction of acetoin with anhydrous HCN appears to be stere