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Application of ion-exchange resin coated plates for thin-layer chromatography of sulfonamides and some other chemotherapeutic compounds

✍ Scribed by Pauncz, Judit Kádár


Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
290 KB
Volume
4
Category
Article
ISSN
0935-6304

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✦ Synopsis


Abstract

A thin‐layer chromatographic method is described for sulfonamides and some other chemotherapeutic compounds. Ion‐exchange resin precoated plates (Fixion 50 × 8 Na^+^, Chinoin, Budapest or Polygram Ionex‐25 SA‐Na, Macherey‐Nagel and Co.,Düren, FRG) are employed with Na~2~HPO~4~ or Na‐acetate (adjusted to different pH values) containing NaCl and tert‐butyl alcohol or ethanol as developing solvent system. For qualitative and/or semiquantitave determinations the chromatograms can be stained: (A) with o‐tolidine, after chlorination; (B) with p‐dimethylaminobenzaldehyde; (C) with p‐dimethylaminocinnamaldehyde.