Application of imiquimod by suppositories (anal tampons) efficiently prevents recurrences after ablation of anal canal condyloma
✍ Scribed by M. Kaspari; R. Gutzmer; T. Kaspari; A. Kapp; J.P. Brodersen
- Book ID
- 104460285
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 88 KB
- Volume
- 147
- Category
- Article
- ISSN
- 0007-0963
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✦ Synopsis
Background:
After surgical removal, anal canal condyloma (acc) has a higher risk of recurrence compared with extragenital warts.
Objectives:
To reduce local recurrences of acc using follow-up treatment with imiquimod-containing suppositories (anal tampons).
Methods:
After ablation of acc, 10 male patients received treatment with imiquimod suppositories three times weekly for 3-4 months.
Results:
Treatment with imiquimod anal tampons was well tolerated. early initial recurrences in some patients cleared after treatment with the imiquimod suppositories. within a mean follow-up of 9 months no patient demonstrated recurrence of acc.
Conclusions:
These data suggest that imiquimod anal tampons may represent a new therapeutic option to prevent recurrences of acc following ablative surgery.