Application of high-pressure gas chromatography with columns packed with small particles

✍ Scribed by H.H. Lauer; H. Poppe; J.F.K. Huber

• Book ID: 104144372
• Publisher: Elsevier Science
• Year: 1977
• Tongue: English
• Weight: 980 KB
• Volume: 132
• Category: Article
• ISSN: 1873-3778
• DOI: 10.1016/s0021-9673(00)93765-8

✦ Synopsis

The application of high-pressure gas chromatography using columns with an I.D. of 1 .O mm, packed with small porous particles (below 60 pm), coated with a nonpolar or polar stationary liquid, is described.

Plots of the theoretical plate height as a function of the mobile phase velocity demonstrate the Iow mixing characteristics of this type of column. A linear relationship was found between the number of theoretical plates and column length at a high ratio of the inlet and outlet pressures; 55,000 theoretical plates could be achieved at an inlet pressure of 44 bar with a 6-m long column.

For use in solving separation problems by gas chromatography, a nomogram has been derived that enables the proper conditions to be chosen. Some chromatograms that demonstrate the potential of these columns are presented.

Finally, an example of the dependence of the retention behaviour on the average column pressure is shown.