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Application of high-performance liquid chromatography and thermospray high-performance liquid chromatography-mass spectrometry to the analysis and identification of 2′,3′-dideoxyadenosine and its metabolite in biological media

✍ Scribed by Patricia A. Blau; John W. Hines; Robert D. Voyksner


Publisher
Elsevier Science
Year
1987
Weight
773 KB
Volume
420
Category
Article
ISSN
0378-4347

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✍ Antonio Triolo; Fabio Bonelli; Orenzo Agostini; Graziano Bonacchi; Emilio Toja 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 652 KB

## Abstract The metabolism of MX/2/120, a new xanthine derivative endowed with potent and long‐lasting antibronchospastic activity, was investigated in guinea‐pig urine, plasma and bile after intravenous administration of 12.5 mg kg^−1^ by high‐performance liquid chromatography/tandem mass spectrom