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Application of FISH to complex chromosomal rearrangements associated with chronic myelogenous leukemia

โœ Scribed by Beth A. Sullivan; Charles A. Schiffer; Shivanand R. Paril; Dennis Hulseberg; Julie Leana-Cox; Stuart Schwartz

Book ID
113253310
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
468 KB
Volume
82
Category
Article
ISSN
0165-4608

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Philadelphia chromosome-negative chronic
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โœ Jorge E. Cortes; Moshe Talpaz; Miloslav Beran; Susan M. O'Brien; Mary B. Rios; S ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 594 KB

Background. Five to 10% of patients with chronic myelogenous leukemia (CML) do not have the Philadelphia chromosome (Ph), but one-third of them have rearrangements of the breakpoint cluster region (BCR-positive). Methods. The authors analyzed the characteristics, treatment response, and prognosis o