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Application of Epigenome-Modifying Small Molecules in Induced Pluripotent Stem Cells

✍ Scribed by Junyan Lu; Xiangqian Kong; Cheng Luo; Keqin Kathy Li


Book ID
111676976
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
901 KB
Volume
33
Category
Article
ISSN
0198-6325

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The team of Liu et al. generated endoderm-derived human induced pluripotent stem (iPS) cells from primary hepatocytes. 1 However, they generated human iPS cells by using viral transgenes. 1 Clinical applications of human iPS cells require avoiding viral transgenes. On the other hand, the reprogrammi