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Application of differential cDNA screening techniques to the identification of unique gene expression in tumours and lymphocytes

✍ Scribed by Jochen Hess; Helmut Laumen; Thomas Wirth

Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 578 KB
Volume: 10
Category: Article
ISSN: 0952-7915
DOI: 10.1016/s0952-7915(98)80239-2

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✦ Synopsis

In this review, we will briefly summarise the principles, advantages and disadvantages of the various strategies. The main aim is to summarise recent applications of these methods; however, we will focus on specific advances made by this methodology in our understanding of lymphopoiesis and tumorigenesis. Comparing PCR-based and sequence-based approaches, it becomes clear that both strategies will remain invaluable for some years to come.

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