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Application of chiral N,N′-dialkyl-1,2-cyclohexanediamine derivatives in asymmetric copper(II)-catalyzed Henry reactions

✍ Scribed by Chunhong, Zhao; Liu, Fei; Gou, Shaohua


Book ID
121700907
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
803 KB
Volume
25
Category
Article
ISSN
0957-4166

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Synthesis of Chiral 1,3-Diamines Derived
✍ Dr. Koichi Kodama; Kazuyuki Sugawara; Prof. Takuji Hirose 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 438 KB 👁 1 views

## Abstract In this study, 13 different chiral 1,3‐diamines were synthesized from (−)‐__cis__‐2‐benzamidocyclohexanecarboxylic acid. They were successfully applied as ligands in the Cu‐catalyzed asymmetric Henry reaction between benzaldehyde and nitromethane. It was confirmed that the enantioselect