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Application of capillary electrophoresis to the quality control of pharmaceutical formulations: Effect of area correction on quantitation of antitussives

✍ Scribed by Milos Korman; Johan Vindevogel; Pat Sandra

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 389 KB
Volume: 5
Category: Article
ISSN: 1040-7685
DOI: 10.1002/mcs.1220050606

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✦ Synopsis

Abstract

The application of capillary electrophoresis for assaying the drug content of pharmaceutical formulations has been studied. Correction of area for migration times has been found useful in those cases where environmental conditions lead to increased migration time variability. From the results, the feasibility of single‐point calibration with an external standard was shown and experimentally verified.

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Application of micellar electrokinetic chromatography to the quality control of pharmaceutical formulations: The analysis of xanthine derivatives

✍ Milos Korman; Dr. Johan Vindevogel; Pat Sandra 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 437 KB

## Abstract Micellar electrokinetic chromatography (MEKC) has been applied to the analysis of three different drugs. Although belonging to different therapeutic classes, all these drugs contain xanthine derivatives as active substances. Pen‐toxifylline was separated from eight related xanthines. Qu