Application of brain microdialysis to study the pharmacology of the 5-HT1A autoreceptor
β Scribed by Trevor Sharp; Stephan Hjorth
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 659 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0165-0270
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π SIMILAR VOLUMES
Hippocampal serotonin (5-hydroxytryptamine, 5-HT) synthesis, as determined by the accumulation of 5-hydroxytryptophan (5-HTP) following inhibition of L-aromatic amino acid decarboxylase with NSD 1015, was inhibited by systemic administration of the selective serotonin reuptake inhibitors fluoxetine
The present study investigated alterations of the regulation of serotonin (5-hydroxytryptamine; 5-HT) release by 5-HT 1A autoreceptors following single and repeated treatment with the 5-HT 1A receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). Rats were pretreated with 8-OH-DPAT (1.