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Application of Atelocollagen-Mediated siRNA Delivery for RNAi Therapies

✍ Scribed by Kimi Honma; Fumitaka Takeshita; Takahiro Ochiya

Book ID
102009587
Publisher
John Wiley and Sons
Year
2007
Weight
11 KB
Volume
38
Category
Article
ISSN
0931-7597

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## Abstract The largest obstacle to the effective use of short interfering RNA (siRNA) in an animal body is the ability to deliver it to the target tissue. Here we showed a systemic delivery method of siRNA specific to pregrown solid tumors __via__ atelocollagen. Atelocollagen facilitated the selec