## Abstract Stepwise synthetic assembly of polypeptide chains reversibly linked to polyethylene glycol represents a hybrid between traditional solution and solid‐phase chemistries and combines the inherent advantages of both approaches. The technical simplicity and scalability of the liquid‐phase p
✦ LIBER ✦
Application of arylsulphonyl side-chain protected arginines in solid-phase peptide synthesis based on 9- fluorenylmethoxycarbonyl amino protecting strategy
✍ Scribed by FISCHER, PETER M. ;RETSON, KIM V. ;TYLER, MARGARET I. ;HOWDEN, MERLIN E.H.
- Book ID
- 115099291
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Tongue
- English
- Weight
- 447 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0367-8377
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## Abstract The sequence‐dependent, acid‐ or base‐catalysed aspartimide formation is one of the most serious side reactions in solid‐phase synthesis of peptides containing aspartic acid. In the present work, we investigated the susceptibility of 4‐{__N__‐[1‐(4,4‐dimethyl‐2,6‐dioxocyclohexylidene)‐3