Abstract
Quantitative total ionic analysis of alcoholic and nonalcoholic beverages was performed by microchip capillary electrophoresis with external contactless conductivity detection. An electrolyte solution consisting of 10.5 mM histidine, 50 mM acetic acid, and 2 mM 18‐crown‐6 at pH 4.1 was used for the determination of NH~4~^+^, K^+^, Ca^2+^, Na^+^, and Mg^2+^. Fast analysis of Cl^−^, NO~3~^−^, and SO~4~^2−^ was achieved in 20 mM 2‐(N‐morpholino)ethanesulfonic acid /histidine electrolyte solution at pH 6.0 and the simultaneous separation of up to 12 inorganic and organic anions was performed in a solution containing 10 mM His and 7 mM glutamic acid at pH 5.75. Limits of detection ranged from 90 to 250 μg/L for inorganic cations and anions, and from 200 to 2000 μg/L for organic anions and phosphate. Calibration curves showed linear dependencies over one to two orders of magnitude when the stacking effect was minimized by injecting standard solutions prepared in background electrolyte solutions. Total analysis times of 35 and 90 s were achieved for the determination of 5 inorganic cations and for the simultaneous determination of 12 inorganic and organic anions, respectively, which represents a considerable reduction of analysis time compared to conventional separation methods used in food analysis.