✦ LIBER ✦
Application of allylpalladium intermediate to a simple stereoselective synthesis of (±)-1-hydroxy-trans-8-dodecenoic acid, a precursor of naturally occurring macrolide from cephalosporium recifei
✍ Scribed by Jiro Tsuji; Tomio Yamakawa; Tadakatsu Mandai
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- French
- Weight
- 204 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
Palladium-catalyzed telomerization of butadiene with various nucleophiles offers a number of useful compounds.
1 In our continuous effort to utilize these compounds for natural product syntheses, we have already synthesized Matsutake alcohol, 2,3 2,15-hexadecanedione,4 royal jelly acids, 5,6 queen substance, 7
pellitorine, 8 and civetone. 9 Another elegant application is the synthesis of brevicomin by Byron. 10 We now wish to report the application of the palladium