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Application of a comprehensive subtelomere array in clinical diagnosis of mental retardation

✍ Scribed by Klaas Kok; Trijnie Dijkhuizen; Yolanthe E. Swart; Hanny Zorgdrager; Pieter van der Vlies; Rudolf Fehrmann; Gerard J. te Meerman; Klasien B.J. Gerssen-Schoorl; Ton van Essen; Birgit Sikkema-Raddatz; Charles H.C.M. Buys


Book ID
116432795
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
375 KB
Volume
48
Category
Article
ISSN
1769-7212

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Subtelomeric rearrangements in the menta
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In recent years, subtelomeric rearrangements, e.g., chromosome deletions or duplications too small to be detected by conventional cytogenetic analysis, have emerged as a significant cause of both idiopathic and familial mental retardation. As mental retardation is a common disorder, many patients ne