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Appearance of resistance to beta-lactam antibiotics during therapy for Streptococcus pneumoniae meningitis

✍ Scribed by M. Muñoz; E.S. Valderrabanos; E. Diaz; J.J. Silva; J.A. Soult; P. Infante; J.D. Lopez; A. Garcia-Curiel

Book ID
117164869
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
177 KB
Volume
127
Category
Article
ISSN
1097-6833

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Penicillin-binding proteins (PBPs) catalyze the transpeptidase reaction involved in peptidoglycan synthesis and are covalently inhibited by the ␤-lactam antibiotics. In a previous work we have focused on acylation efficiency measurements of various Streptococcus pneumoniae PBP2x\* mutants to study t