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Apoptotic pathway induced by transduction of RUNX3 in the human gastric carcinoma cell line MKN-1

✍ Scribed by Yumi Nagahama; Mika Ishimaru; Mitsuhiko Osaki; Toshiaki Inoue; Akihiro Maeda; Chisato Nakada; Masatsugu Moriyama; Kenzo Sato; Mitsuo Oshimura; Hisao Ito


Book ID
108584045
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
306 KB
Volume
0
Category
Article
ISSN
1347-9032

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✍ Tracy Lessor; Joo-Yeon Yoo; Myrtle Davis; Anne W. Hamburger πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 121 KB πŸ‘ 1 views

The AU565 breast carcinoma cell line was used to determine the role of the extracellular-regulated kinase (ERK) pathway in mediating Heregulin␀1 (HRG␀1)-induced mammary cell differentiation. ERK activation remained elevated for 2 h following high doses of HRG which induce differentiation. In contras