𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Apoptotic effects of imidazo[1,2-a]pyrazine derivatives in the human Dami cell line

✍ Scribed by Katja Zurbonsen; Alain Michel; Pierre-Antoine Bonnet; Leila Gannoun-Zaki; Marie-Noëlle Mathieu; Claude Chevillard


Book ID
117099031
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
356 KB
Volume
320
Category
Article
ISSN
0014-2999

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Structure-based design of imidazo[1,2-a]
✍ Nathalie Bouloc; Jonathan M. Large; Magda Kosmopoulou; Chongbo Sun; Amir Faisal; 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 879 KB

Co-crystallisation of the imidazo[1,2-a]pyrazine derivative 15 (3-chloro-N-(4-morpholinophenyl)-6-(pyridin-3-yl)imidazo[1,2-a]pyrazin-8-amine) with Aurora-A provided an insight into the interactions of this class of compound with Aurora kinases. This led to the design and synthesis of potent Aurora-