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Apoptotic cells, autoantibodies, and the role of HMGB1 in the subcellular localization of an autoantigen

✍ Scribed by Amy N. Sanford; Kelly Dietzmann; Kathleen E. Sullivan


Book ID
116613955
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
566 KB
Volume
25
Category
Article
ISSN
0896-8411

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## Abstract High‐mobility group box–1 (HMGB1) was originally identified as a ubiquitously expressed, abundant nonhistone DNA‐binding protein. Recently, it was found to act as a cytokine‐like mediator of delayed endotoxin lethality and of acute lung injury. Previously, we reported that HMGB1 is mass