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Apoptotic cells and clonally expanded cytotoxic T cells in bone marrow trephines of patients with myelodysplastic syndrome

✍ Scribed by Heinke Pülhorn; Martin Herrmann; Harry Harms; Andreas Jung; Irith Baumann

Book ID
114729169
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
392 KB
Volume
61
Category
Article
ISSN
0309-0167

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## Abstract Polymyositis is a CD8^+^ T‐cell–mediated disease. T‐cell clonal expansions are observed at disease onset, but little is known about their persistence over time. Qualitative and quantitative spectratyping demonstrated that PM relapse features dramatically perturbed blood T‐cell repertoir