## Abstract The combination of 2β²βdeoxyadenosine and 2β²βdeoxycoformycin is toxic for the human colon carcinoma cell line LoVo. In this study we investigated the mode of action of the two compounds and have found that they promote apoptosis. The examination by fluorescence microscopy of the cells tr
Apoptotic cell death and its relationship to carcinogenesis in colorectal carcinoma
β Scribed by Shunichi Tsujitani; Hiroyuki Shirai; Shigeru Tatebe; Kenji Sugamura; Satoshi Ohfuji; Yoshihito Gomyo; Michio Maeta; Hisao Ito; Nobuaki Kaibara
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 668 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0008-543X
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β¦ Synopsis
BACKGROUND.
Apoptotic cell death plays an important role in the proliferation and turnover of cells in various tumors. The relationship between apoptosis and cell proliferation was studied to determine each of their roles in colorectal carcinogenesis.
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