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Apoptotic and anti-proliferative effects of 17β-estradiol and 17β-estradiol-like compounds in the Hep3B cell line

✍ Scribed by Erh-Jung Huang; Cheng-Chung Wu; Hsien-Ping Huang; Jer-Yuh Liu; Chung-Sheng Lin; Yan-Zin Chang; James A. Lin; Jaung-Geng Lin; Li-Mien Chen; Shin-Da Lee; Wei-Wen Kuo; Chih-Yang Huang

Publisher: Springer
Year: 2006
Tongue: English
Weight: 331 KB
Volume: 290
Category: Article
ISSN: 0300-8177
DOI: 10.1007/s11010-005-9000-y

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## Abstract A human ovarian adenocarcinoma cell line (PE04) has been established as a xenograft in nude mice. __In vitro__, this cell line is estrogen receptor (ER)‐positive and its growth is stimulated by 17 β‐estradiol at concentrations between 10^−12^ and 10^−6^ M. When xenografted, PE04 cells r