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Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis

✍ Scribed by Clarke, Murray C H; Figg, Nichola; Maguire, Janet J; Davenport, Anthony P; Goddard, Martin; Littlewood, Trevor D; Bennett, Martin R


Book ID
109932898
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
704 KB
Volume
12
Category
Article
ISSN
1078-8956

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✍ Cyril M. Pilane; Edward F. LaBelle πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 218 KB πŸ‘ 1 views

## Abstract We have shown previously that nitric‐oxide (NO) can induce apoptosis of vascular smooth muscle cells (VSMCs) and that the NO‐induced apoptosis is accompanied by an increase in arachidonic acid release via cytoplasmic Ca^2+^‐dependent phospholipase A~2~ (cPLA~2~). We have evidence that d