Apoptosis of human fibrosarcoma HT-1080 cells by epigallocatechin-3-O-gallate via induction of p53 and caspases as well as suppression of Bcl-2 and phosphorylated nuclear factor-κB

Arsenic trioxide (As2O3) inhibits invasi

Arsenic trioxide (As2O3) inhibits invasion of HT1080 human fibrosarcoma cells: Role of nuclear factor-κB and reactive oxygen species

✍ Myung-Jin Park; Jae-Young Lee; Hee-Jin Kwak; Chang-Min Park; Hyung-Chahn Lee; Sa 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 487 KB

## Abstract In order to define the role of As~2~O~3~ in regulating the tumor cell invasiveness, the effects of As~2~O~3~ on secretion of matrix metalloproteinases (MMPs) and urokinase plasminogen activator (uPA), and in vitro invasion of HT1080 human fibrosarcoma cells were examined. As~2~O~3~ inhi