𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Apoptosis of human endothelial cells is accompanied by proteolytic processing of latent TGF-β binding proteins and activation of TGF-β

✍ Scribed by Solovyan, V T; Keski-Oja, J

Book ID
110016929
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
297 KB
Volume
12
Category
Article
ISSN
1350-9047

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Proteolytic activation of latent TGF-β p
Proteolytic activation of latent TGF-β precedes caspase-3 activation and enhances apoptotic death of lung epithelial cells
✍ Victor T. Solovyan; Jorma Keski-Oja 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 380 KB

## Abstract Transforming growth factors β (TGF‐βs) are multifunctional cytokines, which are secreted in latent forms in large latent TGF‐β complexes (LL‐TGF‐β) with subsequent deposition to the extracellular matrix (ECM). While a variety of mechanisms capable of activating latent TGF‐β in vitro hav

TGF-β1–dependent differential expression
TGF-β1–dependent differential expression of a rat homolog for latent TGF-β binding protein in astrocytes and C6 glioma cells
✍ Knut Krohn 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 338 KB 👁 1 views

Transforming growth factor-beta1 (TGF-beta1) is widely recognized for its multiple roles in development, cellular maintenance, and protection against injury. In the brain, TGF-beta1 upregulation in microglia/macrophages is a predominant response to lesion and during pathology. However, the precise f

Membrane protein GARP is a receptor for
Membrane protein GARP is a receptor for latent TGF-β on the surface of activated human Treg
✍ Julie Stockis; Didier Colau; Pierre G. Coulie; Sophie Lucas 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 369 KB

Human Treg and Th clones secrete the latent form of TGF-b, in which the mature TGF-b protein is bound to the latency-associated peptide (LAP), and is thereby prevented from binding to the TGF-b receptor. We previously showed that upon TCR stimulation, human Treg clones but not Th clones produce acti

Subcellular localization of (latent) tra
Subcellular localization of (latent) transforming growth factor β and the latent TGF-β binding protein in rat hepatocytes and hepatic stellate cells
✍ Sylke Roth-Eichhorn; Kitty Kühl; Axel M. Gressner 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 754 KB

Recently, the existence of the large latent transforming growth factor ␤ (TGF-␤) complex, consisting of TGF-␤, the N-terminal part of its precursor (latency-associated peptide [LAP]), and the latent TGF-␤ binding protein (LTBP), was demonstrated in rat liver parenchymal cells (PC) and stellate cells