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Apoptosis is induced by decline of mitochondrial ATP synthesis in erythroleukemia cells

✍ Scribed by Marina Comelli; Francesca Di Pancrazio; Irene Mavelli


Book ID
114275529
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
183 KB
Volume
34
Category
Article
ISSN
0891-5849

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Strikingly increased expression of notch-1 has been demonstrated in several human malignancies and pre-neoplastic lesions. However, the functional consequences of notch-1 overexpression in transformed cells remain unclear. We investigated whether endogenously expressed notch-1 controls cell fate det