Apoptosis induced by baicalin involving up-regulation of P53 and bax in MCF-7 cells
β Scribed by Wang, Ning; Tang, Li-Jian; Zhu, Guo-Qi; Peng, Dai-Yin; Wang, Lei; Sun, Fa-Neng; Li, Qing-Lin
- Book ID
- 120265358
- Publisher
- Taylor and Francis Group
- Year
- 2008
- Tongue
- English
- Weight
- 736 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1028-6020
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## Abstract Jurkat Tβlymphocytes lack p53 and Bax but contain p73 and Bid and are killed by etoposide (ETO). With ETO cβabl is phosphorylated and phosphorylated p73 increased. Translocation of fullβlength Bid to mitochondria follows, with induction of the mitochondrial permeability transition (MPT)