Apoptosis in the vascular wall and atherosclerosis
✍ Scribed by Lothar Rössig; Stefanie Dimmeler; Andreas M. Zeiher
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 398 KB
- Volume
- 96
- Category
- Article
- ISSN
- 0300-8428
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## Abstract The vascular cell apoptosis may play an important role in the development of atherosclerosis. Reticulons, the only molecular so far to participate in all three apoptosis signaling pathways, may be a novel player in the progress of AS. We presumes that reticulons may belong to the princi
Normal arteries are characterized by a low turnover of endothelial (EC) and smooth muscle cells (SMC). Different mechanisms protect the EC and SMC against apoptosis in the normal artery. In hypertension, SMC replication is increased but this is not counterbalanced by increased apoptosis, resulting i