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Apoptosis in the development and maintenance of the immune system

✍ Scribed by Opferman, Joseph T.; Korsmeyer, Stanley J.


Book ID
109921306
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
598 KB
Volume
4
Category
Article
ISSN
1529-2908

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T he development of immune defense mecha- nisms begins early during fetal life but is not completely achieved at birth, leading to a peculiar susceptibility of the neonate to infectious diseases. 1,2 The earliest hematopoietic stem cells are detectable in the yolk sac around 6 weeks of gestation, bu