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Apoptosis bcl-2 and p53 expression and their relation to tumour stage in non-small cell lung carcinomas (NSCLC)

✍ Scribed by H.Aydanur Kargi; Safiye Aktaş; Özgül Sağol; Sülün Ermete; Oya Akpinar; Atilla Akkoçlu


Book ID
117468513
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
118 KB
Volume
116
Category
Article
ISSN
0304-3835

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We analyzed a set of 103 non-small cell lung carcinomas (NSCLCs) for caspase-3, -6 and -8 expression and apoptosis. Additionally, the expression of bcl-2, bax and p53 were studied. Caspase-3 positivity appeared as diffuse, cytoplasmic staining and was restricted to the tumor area. In contrast, the i