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Apoptosis and nitric oxide in an experimental model of osteoarthritis in rabbit after hyaluronic acid treatment

✍ Scribed by Luis Díaz-Gallego; Julio G. Prieto; Pilar Coronel; Luis E. Gamazo; Mercedes Gimeno; Ana I. Alvarez


Book ID
113834672
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
354 KB
Volume
23
Category
Article
ISSN
0736-0266

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## Abstract We investigated whether __N__‐acetylcysteine (NAC), a precursor of glutathione, could protect rabbit articular chondrocytes against nitric oxide (NO)‐induced apoptosis and could prevent cartilage destruction in an experimental model of osteoarthritis (OA) in rats. Isolated chondrocytes