Apoptosis and ductal plate malformation in meckel syndrome
โ Scribed by P. Kahl; C. Sergi; H.F. Otto
- Book ID
- 118564521
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 272 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0168-8278
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## Abstract The Meckel syndrome (MS) is an autosomal recessive disorder classically defined by the triad of occipital encephalocele, multicystic kidneys, and polydactyly. Here we describe 3 sibs with varying manifestations of MS. The propositus had isolated cystic renal disease. The other sibs were
The Meckel syndrome is an autosomal recessive condition and includes a heterogeneous group of CNS malformations, most frequently occipital encephalocele. We report on 2 sibs and one other unrelated case with Meckel syndrome in whom the CNS anomaly was the Dandy-Walker malformation, an association no
In six fetuses with Meckel syndrome (gestational age 16-23 weeks, crown-rump length 130-170 mm) the skeleton was examined as part of the autopsy procedure using whole body radiography and special radiographic techniques. In the upper and lower limbs we found similar types of polydactyly. We noted fo