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Apomorphine and amphetamine stereotypy after 6-hydroxydopamine lesions of the substantia nigra

✍ Scribed by Marion T.C. Price; Hans C. Fibiger

Book ID
118321386
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
282 KB
Volume
29
Category
Article
ISSN
0014-2999

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Apomorphine-induced yawning in rats is a
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Apomorphine-induced yawning was studied in male rats with bilateral 6-hydroxydopamine lesions of the substantia nigra. Apomorphine 10, 20 and 50 lag/kg SC induced dose-dependent yawning in unoperated controls and animals with sham lesions. In the lesioned animals (in which the mean striatal dopamine

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The activity of neurons in the subthalamic nucleus (STN) of the behaving rat, before and after a unilateral 6-OHDA lesion of the substantia nigra, was recorded with the extracellular technique to determine whether it was altered following systemic amphetamine, 5 mg/kg, apomorphine, 3 mg/kg, and apom