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Apoliprotein-E is increased in Alzheimer's disease synapses and associates with amyloid beta

✍ Scribed by Karen H. Gylys; Stephen P. Arold; Kristen M. Henkins; Wayne Poon; Carol A. Miller; Harry V. Vinters; Greg M. Cole

Book ID
118466253
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
47 KB
Volume
6
Category
Article
ISSN
1552-5260

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πŸ“œ SIMILAR VOLUMES

APOLIPOPROTEIN E IS ASSOCIATED WITH ISLE
APOLIPOPROTEIN E IS ASSOCIATED WITH ISLET AMYLOID AND OTHER AMYLOIDOSES: IMPLICATIONS FOR ALZHEIMER'S DISEASE
✍ CHARGΓ‰, SOPHIE B. P.; ESIRI, MARGARET M.; BETHUNE, CLAIRE A.; HANSEN, BARBARA C. πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 652 KB

Apolipoprotein E (ApoE) has recently been proposed as an aetiological factor of Alzheimer's disease (AD): ApoE is co-localized to amyloid plaques and neurofibrillary tangles in the brain and binds to AP-protein in vitvo. An association of ApoE e4 allele with the development of AD has been reported.