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ApolipoproteinE mimetic peptides improve outcome after focal ischemia

✍ Scribed by Wang, Haichen; Anderson, Lauren G.; Lascola, Christopher D.; James, Michael L.; Venkatraman, Talaignair N.; Bennett, Ellen R.; Acheson, Shawn K.; Vitek, Michael P.; Laskowitz, Daniel T.

Book ID
120593961
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
871 KB
Volume
241
Category
Article
ISSN
0014-4886

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## Abstract Apolipoprotein E (apoE) is the primary apolipoprotein synthesized in the brain in response to injury with known neuroprotective effects exerted through antioxidant, antiinflammatory, antiexcitotoxic, and neurotrophic mechanisms. We have previously demonstrated that COG1410, an apoE mime