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Apolipoprotein(a) phenotypes in cardio-cerebrovascular diseases

✍ Scribed by Zhuang Yiyi; Li Janjun; Wang Junjun

Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
266 KB
Volume
67-68
Category
Article
ISSN
0009-3084

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✦ Synopsis

We report apolipoprotein(a) (apo(a)) phenotypes of 69 myocardial infarction survivors and 56 stroke patients, and compare them with those of 190 healthy Chinese. The results indicate that the distribution of apo(a) phenotype frequency in cardio-cerebrovascular disease patients is different from those of controls. The frequency of the phenotypes B, SI and S 2 in patients is remarkably higher than those in controls within the same single-band apo(a) phenotype. Moreover, the Lp(a) serum concentrations in CCVD patients are significantly higher than those in controls within the same single-band apo(a) phenotype. The apo(a) phenotype analyses of two pedigrees are shown as a typical autosomal dominant inheritance.

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