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Apolipoprotein E2 (ARG136 - > CYS): detection of a new frequent apo E mutation in a German population

✍ Scribed by W. März; E. Fisher; U. Stein; M. Chen; W. Groβ; H. Wieland


Book ID
118325871
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
111 KB
Volume
115
Category
Article
ISSN
0021-9150

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## Communicated by Michel Goossens Familial ligand-defective apolipoprotein B-100 (FDB) is an autosomal dominant disorder leading to plasma LDL cholesterol elevation and coronary artery disease (CAD). Two specific mutations in the APOB gene-R3500Q and R3531C-induce FDB. We report an original metho