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Apolipoprotein E isoforms and regulation of the innate immune response in brain of patients with Alzheimer's disease

✍ Scribed by C Dirk Keene; Eiron Cudaback; Xianwu Li; Kathleen S Montine; Thomas J Montine

Book ID: 113553170
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 471 KB
Volume: 21
Category: Article
ISSN: 0959-4388
DOI: 10.1016/j.conb.2011.08.002

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## Abstract The etiology of late‐onset Alzheimer disease is poorly understood. Predisposing factors such as the apolipoprotein E4 allele, as well as protective factors (e.g., antioxidants) have been proposed to play a role in the disease's process. A search for predisposing factors contributing to