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Apolipoprotein E (apoE) isoforms differentially induce nitric oxide production in endothelial cells

โœ Scribed by Sandra M Sacre; Anita K Stannard; James S Owen


Book ID
117105261
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
204 KB
Volume
540
Category
Article
ISSN
0014-5793

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Nitric oxide (NO) produced by endothelial cells (EC) has been shown to exert cytotoxic activity on tumor cells. In order to analyze events involved in brain metastasis, the modulation of N O production in rat-brain-derived EC was investigated. N O release was increased by tumor necrosis factor-a (TN