## Abstract ## Objective This crossβsectional study examined the relationship between subjective memory complaints and the apolipoprotein epsilon 4 allele (Ξ΅4), a genetic risk factor for Alzheimer's disease (AD), among cognitively normal subjects identified from a community memory screening. ## D
Apolipoprotein E and cognitive change in an elderly population
β Scribed by Dr. B. T. Hyman; T. Gomez-Isla; M. Briggs; H. Chung; S. Nichols; F. Kohout; R. Wallace
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 967 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
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## Abstract Alzheimer's Disease (AD) is a complex genetic disorder with four loci already identified. Mutations in three of these, the amyloid precursor protein, presenilin I, and preseuilin II, cause earlyβonset AD. The apolipoprotein E (APOE) gene contributes primarily to lateβonset AD. The APOEβ