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Apolipoprotein E-4 gene dose in clinically diagnosed Alzheimer's disease: prevalence, plasma cholesterol levels and cerebrovascular change

✍ Scribed by C. Czech; H. Förstl; F. Hentschel; U. Mönning; C. Besthorn; C. Geiger-Kabisch; H. Sattel; C. Masters; K. Beyreuther

Book ID
105491255
Publisher
Springer-Verlag
Year
1994
Tongue
English
Weight
188 KB
Volume
243
Category
Article
ISSN
1433-8491

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Gene dose of the ε4 allele of apolipopro
Gene dose of the ε4 allele of apolipoprotein E and disease progression in sporadic late-onset alzheimer's disease
✍ Dr Giovanni B. Frisoni; Stefano Govoni; Cristina Geroldi; Angelo Bianchetti; Lau 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 974 KB

A strong association has been described in cross-sectional studies between the ~4 allele of the apolipoprotein E and late-onset Alzheimer's disease (LOAD). This study addresses the relationship between disease progression and the ~4 allele in 6 2 sporadic LOAD (onset at age 70 and over) patients. Di