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Apolipoprotein A-IV polymorphism in man

✍ Scribed by Hans-Jürgen Menzel; Michael Kövary; Gerd Assmann

Book ID
104714675
Publisher
Springer
Year
1982
Tongue
English
Weight
853 KB
Volume
62
Category
Article
ISSN
0340-6717

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Human apolipoprotein (apo) A-IV is genetically polymorphic, the apo A-IV polymorphism being controlled by two common alleles, A-IV1 and A-IV2. We have developed a method for typing the apo A-IV polymorphism by Western blotting using polyclonal rabbit antiapo A-IV as the first and gold-labeled antira

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Apolipoprotein A-IV phenotypes were determined by reprobing immunoblots initially typed for the apolipoprotein E polymorphism on a representative sample of Mexican-Americans from South Texas. Typings on 331 individuals gave frequency estimates of 0.928, 0.066, 0.003, and 0.003 for alleles 1, 2, 3, a