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APOE genotype and extent of bleeding and outcome in lobar intracerebral haemorrhage: a genetic association study

✍ Scribed by Alessandro Biffi; Christopher D Anderson; Jeremiasz M Jagiella; Helena Schmidt; Brett Kissela; Björn M Hansen; Jordi Jimenez-Conde; Caroline R Pires; Alison M Ayres; Kristin Schwab; Lynelle Cortellini; Joanna Pera; Andrzej Urbanik; Javier M Romero; Natalia S Rost; Joshua N Goldstein; Anand Viswanathan; Alexander Pichler; Christian Enzinger; Raquel Rabionet; Bo Norrving; David L Tirschwell; Magdy Selim; Devin L Brown; Scott L Silliman; Bradford B Worrall; James F Meschia; Chelsea S Kidwell; Joseph P Broderick; Steven M Greenberg; Jaume Roquer; Arne Lindgren; Agnieszka Slowik; Reinhold Schmidt; Daniel Woo; Jonathan Rosand

Book ID: 114409846
Publisher: The Lancet
Year: 2011
Tongue: English
Weight: 157 KB
Volume: 10
Category: Article
ISSN: 1474-4465
DOI: 10.1016/s1474-4422(11)70148-x

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## Abstract Estimation and testing of genetic effects (genotype relative risks) are often performed conditionally on parental genotypes, using data from case‐parent trios. This strategy avoids having to estimate nuisance parameters such as parental mating type frequencies, and also avoids generatin