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Apocalmodulin and Ca 2+ Calmodulin Bind to the Same Region on the Skeletal Muscle Ca 2+ Release Channel †

✍ Scribed by Moore, Catherine Porter; Rodney, George; Zhang, Jia-Zheng; Santacruz-Toloza, Lucia; Strasburg, Gale; Hamilton, Susan L.


Book ID
126888032
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
108 KB
Volume
38
Category
Article
ISSN
0006-2960

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Optimal [3H]ryanodine binding to skeletal muscle sarcoplasmic reticulum membranes is dependent on a number of factors such as Ca2+ concentration, ionic strength, and the presence of modulators of the Ca2+ release channel. The rate of association of [3H]-ryanodine with its binding site is slower than