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Apicidin, a histone deacetylase inhibitor, induces differentiation of HL-60 cells

โœ Scribed by JangJa Hong; Kenji Ishihara; Kouya Yamaki; Kenji Hiraizumi; Tadao Ohno; Jong Woong Ahn; OkPyo Zee; Kazuo Ohuchi

Book ID
117467549
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
558 KB
Volume
189
Category
Article
ISSN
0304-3835

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This investigation provides evidence that a 60-Hz electromagnetic field (EMF) at 1 gauss (G) can drive differentiation of cultured hematopoietic progenitor cells. HL-60 cells are known to differentiate from a nonphagocytic suspension culture to an attached fibroblast-like culture with high phagocyti