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Apical periodontitis and periodontal disease increase serum IL-17 levels in normoglycemic and diabetic rats

✍ Scribed by Cintra, Luciano Tavares Angelo; Samuel, Renata Oliveira; Azuma, Mariane Maffei; Ribeiro, Clícia Pereira; Narciso, Luis Gustavo; de Lima, Valéria Marçal Felix; Sumida, Dóris Hissako; Coclete, Gilberto Aparecido; Dezan-Júnior, Eloi; Gomes-Filho, João Eduardo

Book ID: 121565929
Publisher: Springer
Year: 2014
Tongue: English
Weight: 284 KB
Volume: 18
Category: Article
ISSN: 1432-6981
DOI: 10.1007/s00784-014-1192-7

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## Background: We analyzed the influence of Crohn's disease (CD)associated IL23R gene variants on IL-22 that is expressed in IL-23Rϩ Th17 cells. Methods: IL-22 serum levels were measured in 242 CD patients and in 31 healthy controls. Subanalyses included serum levels of IL-6, TNF-␣, IL-17A, IL-17