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Aphidicolin allows a rapid and simple evaluation of DNA-repair synthesis in damaged human cells

โœ Scribed by Guido Pedrali-Noy; Silvio Spadari

Book ID
113191757
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
330 KB
Volume
70
Category
Article
ISSN
0027-5107

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DNA repair synthesis of cultured human c
DNA repair synthesis of cultured human cells as a rapid bioassay for chemical carcinogens
โœ R. H. C. San; H. F. Stich ๐Ÿ“‚ Article ๐Ÿ“… 1975 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 541 KB

## Abstract The feasibility of detection of carcinogenic chemicals using DNA repair synthesis of cultured human fibroblasts as measured by an unscheduled ^3^HTdR incorporation has been explored. Of 64 chemicals tested, 29 were proximate or ultimate carcinogens, 15 were precarcinogens that required