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Apelin, an endogenous neuronal peptide, protects hippocampal neurons against excitotoxic injury

✍ Scribed by Lauren A. O’Donnell; Arpita Agrawal; Praveena Sabnekar; Marc A. Dichter; David R. Lynch; Dennis L. Kolson


Book ID
111180239
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
959 KB
Volume
102
Category
Article
ISSN
0022-3042

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## Abstract Although the majority of agents with antiexcitotoxic action act as glutamate receptor antagonists, enzymatic degradation of glutamate can also be neuroprotective. The very low specific activity of the mammalian form of glutamate decarboxylase (GAD), the enzyme that catalyzes the formati